Tsuruselpi S

Tsuruselpi S Uses, Dosage, Side Effects, Food Interaction and all others data.

Tsuruselpi S is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. It is an alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia.

Used to treat hypertension. Tsuruselpi S inhibits angiotensin-converting enzyme. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex and general vasoconstriction, both of which lead to increases vascular resistance. By inhibiting angiotensin II, aldosterone reabsorption is decreased as well as vasoconstriction. This combined effect serves to decrease blood pressure.

Trade Name Tsuruselpi S
Generic Rescinnamine
Rescinnamine Other Names Rescinnamine, Trimethoxy cinnamoyl reserpate de methyl
Type
Formula C35H42N2O9
Weight Average: 634.716
Monoisotopic: 634.289030952
Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Tsuruselpi S
Tsuruselpi S

Uses

For the treatment of hypertension.

How Tsuruselpi S works

Tsuruselpi S Binds to and inhibits the angiotensin converting enzyme. Tsuruselpi S competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in decreased plasma angiotensin II. As angiotensin II is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blood pressure and stimulation of baroreceptor reflex mechanisms, which leads to decreased vasopressor activity and to decreased aldosterone secretion.

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*** Taking medicines without doctor's advice can cause long-term problems.
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