Tussanil-N Uses, Dosage, Side Effects and more
| Attribute | Details |
|---|---|
| Trade Name | Tussanil-N |
| Generic | Noscapine |
| Noscapine Other Names | alpha-Narcotine, Noscapina, Noscapine, Noscapinum |
| Type | |
| Formula | C22H23NO7 |
| Weight | Average: 413.4205 Monoisotopic: 413.147452095 |
| Groups | Approved, Investigational |
| Therapeutic Class | |
| Manufacturer | VIFOR FRIBOURG |
| Available Country | Switzerland |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Tussanil-N is a non-sedating isoquinoline alkaloid used primarily for its antitussive properties.
Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma.
Tussanil-N is also used to associated treatment for these conditions: Common Cold, Cough, Respiratory Diseases, Airway secretion clearance therapy
How Tussanil-N works
Tussanil-N's antitussive effects appear to be primarily mediated by its sigma receptor agonist activity. Evidence for this mechanism is suggested by experimental evidence in rats. Pretreatment with rimcazole, a sigma specific antagonist, causes a dose-dependent reduction in antitussive activity of noscapine.
