UB-612 COVID-19 Vaccine
UB-612 COVID-19 Vaccine Uses, Dosage, Side Effects, Food Interaction and all others data.
The UB-612 COVID-19 Vaccine COVID-19 vaccine was developed by United Biomedical Inc Asia in Taipei as the first COVID-19 “multi-tope” protein-peptide vaccine made up of eight rationally designed components. The vaccine incorporates a strong S1-RBD component linked to a single chain fragment region (sFC) of a human IgG1, which facilitates cell attachment and acts as the principal neutralizing domain of the virus. In addition, the vaccine contains a proprietary peptide UBITh®1a for enhanced immunogenicity, five identified peptides with Th or CTL epitopes to improve peptide solubility, and aluminum phosphate adjuvant. This vaccine was designed to induce a broad immune response. It was able to reduce viral load and prevent COVID-19 infection in a mouse challenge model and in rhesus macaques. In rats, toxicity studies have so far shown favourable safety for this vaccine, Phase 1 trial is currently ongoing in Taiwan (NCT04545749).
| Trade Name | UB-612 COVID-19 Vaccine |
| Generic | UB-612 |
| UB-612 Other Names | UB-612 COVID-19, UB-612 COVID-19 vaccine |
| Type | |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Innovators Monograph
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