Up and Up Tioconazole 1

Up and Up Tioconazole 1 Uses, Dosage, Side Effects, Food Interaction and all others data.

Up and Up Tioconazole 1 interacts with 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability. Up and Up Tioconazole 1 may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms and the uptake of purine, impair triglyceride and/or phospholipid biosynthesis, and inhibit the movement of calcium and potassium ions across the cell membrane by blocking the ion transport pathway known as the Gardos channel.

Up and Up Tioconazole 1 is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Up and Up Tioconazole 1 exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Up and Up Tioconazole 1 prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.

Up and Up Tioconazole 1
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Up and Up Tioconazole 1
Generic	Tioconazole
Tioconazole Other Names	Tioconazol, Tioconazole, Tioconazolum
Type	Vaginal ointment
Formula	C₁₆H₁₃Cl₃N₂OS
Weight	Average: 387.711 Monoisotopic: 385.981416859
Groups	Approved
Therapeutic Class	Drugs used in Vaginal and Vulval condition, Topical Antifungal preparations
Manufacturer
Available Country	United States
Last Updated:	September 19, 2023 at 7:00 am

Uses

Up and Up Tioconazole 1 is used for the local treatment of vulvovaginal candidiasis (moniliasis). As Up and Up Tioconazole 1 has been shown to be effective only for candidal vulvovaginitis, the diagnosis should be confirmed by KOH smears and/or cultures. Other pathogens commonly associated with vulvovaginitis should be ruled out by appropriate methods.

Studies have shown that women taking oral contraceptives have a cure rate similar to those not taking such agents when treated with Up and Up Tioconazole 1.

Up and Up Tioconazole 1 is also used to associated treatment for these conditions: Fungal skin infection, Infection Mixed, Onychomycosis, Skin Infections, Bacterial, Vaginal Candidiasis, Vulvovaginal Candidiasis, Cutaneous dermatophyte infection, Superficial Fungal skin infection

How Up and Up Tioconazole 1 works

Dosage

Up and Up Tioconazole 1 dosage

Topical: Apply & massage gently into the affected & surrounding skin area once or twice a day. In intertriginous areas, apply sparingly & smoothed in well to avoid macerating effects. Duration: 1-6 weeks.

Vaginal candidiasis:

Adult: As 6.5% ointment: Admin intravaginally at bedtime as a single dose.
Child: ≥12 yr Admin at bedtime as a single dose.

Side Effects

Occasional local transient & mild irritation; if hypersensitivity reaction develop, treatment should be discontinued & appropriate therapy should be instituted.

Toxicity

Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning, and general irritation of the skin, and cramps.

Precaution

Not for ophthalmic use.

Food Interaction

No interactions found.

Elimination Route

Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.

Pregnancy & Breastfeeding use

Pregnancy Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

Contraindication

Up and Up Tioconazole 1 is contraindicated in individuals who have been shown to be sensitive to imidazole antifungal agents or to other components of the ointment.

Special Warning

Safety and effectiveness in pregnant and diabetic patients have not been established

Innovators Monograph

You find simplified version here Up and Up Tioconazole 1

Up and Up Tioconazole 1 contains Tioconazole see full prescribing information from innovator Up and Up Tioconazole 1 Monograph, Up and Up Tioconazole 1 MSDS, Up and Up Tioconazole 1 FDA label

FAQ

What is Up and Up Tioconazole 1 used for?

Up and Up Tioconazole 1 is an antifungal medicine. It is used to treat yeast infections of the vagina.

How safe is Up and Up Tioconazole 1?

Both open and controlled clinical trials have clearly demonstrated the efficacy and safety of topical preparations of Up and Up Tioconazole 1 for treating superficial dermatophyte or yeast infections of the skin and vaginal candidiasis.

What is the common side effects of Up and Up Tioconazole 1?

Common side effects may include:

vaginal redness or swelling;
mild stomach pain;
pain or burning when you urinate;
headache, runny or stuffy nose; or.
mild vaginal burning, itching or irritation after use.

Is Up and Up Tioconazole 1 safe during pregnancy?

There are no controlled data in human pregnancy. Even though systemic absorption is insignificant, the manufacturer considers use of the topical solution contraindicated during pregnancy due to the prolonged duration of therapy.

Is Up and Up Tioconazole 1 safe during breastfeeding?

Breastfeeding is not recommended during use of this drug. An alternative agent may be preferred, especially while breastfeeding newborn or preterm infants; the manufacturer recommends nursing women consult a healthcare provider before use of this drug

How long does it take for Up and Up Tioconazole 1 to work?

Up and Up Tioconazole 1 starts working within 5 to 10 hours after being inserted into the vagina. You may see improvement in symptoms within 1 or 2 days after starting this medication.

How do you get Up and Up Tioconazole 1 out of your vagina?

First sit over the toilet and try to push as much of the Up and Up Tioconazole 1 out of your vagina as possible using your vaginal canal muscles. Also lightly wipe up as much of the serum you can with toilet paper, just dab it. Then run a warm bath. Sit in the water and try to flush a much of the ointment out as possible.

How should I use Up and Up Tioconazole 1 vaginal?

Do not take Up and Up Tioconazole 1 vaginal by mouth. It is for use only in your vagina.You should only use this treatment three to four times. If it isn't effective at treating the infection after four applications, see your doctor.

What happens if I overdose?

Since Up and Up Tioconazole 1 vaginal is used as a single dose from a prefilled applicator, an overdose is unlikely to occur.

What should I avoid while using Up and Up Tioconazole 1 vaginal?

Avoid wearing tight-fitting, synthetic clothing such as nylon underwear or panty hose that does not allow air circulation. Wear loose-fitting clothing made of cotton and other natural fibers until your infection is healed.

How long is too long to treat a yeast infection?

More severe yeast infections could take up to 2 weeks to clear without treatment. If your infection is causing painful and uncomfortable symptoms for more than 3 days, you should seek medical treatment.