V1003

V1003 Uses, Dosage, Side Effects, Food Interaction and all others data.

V1003 is an intranasal formulation of buprenorphine, an opiate analgesic, for the management of post-operative pain in hospital and home settings. Buprenorphine is a well-known analgesic and the intranasal formulation has the potential to provide a convenient alternative to other treatments, allowing patients to manage their post-operative pain both prior to discharge from hospital and at home during their recovery period.

Trade Name V1003
Generic V1003
Type
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
V1003
V1003

Uses

Investigated for use/treatment in pain (acute or chronic).

How V1003 works

V1003 is an intranasal formulation of buprenorphine. Buprenorphine's analgesic effect is due to partial agonist activity at mu-opioid receptors. Buprenorphine is also a kappa-opioid receptor antagonist. The partial agonist activity means that opioid receptor antagonists (e.g., an antidote such as naloxone) only partially reverse the effects of buprenorphine. The binding to the mu and kappa receptors results in hyperpolarization and reduced neuronal excitability.

Innovators Monograph

You find simplified version here V1003

*** Taking medicines without doctor's advice can cause long-term problems.
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