Vapreotidum

Vapreotidum Uses, Dosage, Side Effects, Food Interaction and all others data.

Vapreotidum is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.

Vapreotidum is a somatostatin analog with a higher metabolic stability than the parent hormone. Vapreotidum reduces splanchnic blood flow; inhibits growth hormone release, and inhibits the release of peptides and vasoactive compounds from neuroendocrine tumors.

Vapreotidum
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Uses during Pregnancy
Uses during Breastfeeding
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Trade Name	Vapreotidum
Generic	Vapreotide
Vapreotide Other Names	Vapreotida, Vapreotide, Vapreotidum
Type
Formula	C₅₇H₇₀N₁₂O₉S₂
Weight	Average: 1131.38 Monoisotopic: 1130.48301423
Groups	Experimental, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.

How Vapreotidum works

The exact mechanism of action is unknown, although one study has provided in vitro and in vivo evidence for a tachykinin NK1 receptor antagonist effect in the analgesic effects of vapreotide (PMID: 7556407).

Toxicity

Safety data are limited, however, headache, fatigue, diarrhea, nausea, vomiting, and abdominal pain have been reported commonly with the use of vapreotide.