Velzyme
Velzyme Uses, Dosage, Side Effects, Food Interaction and all others data.
Each vial contains: Vitamin B1 (as Thiamine Nitrate): 2.5 mg Vitamin B2 (as Riboflavin Sodium Phosphate): 3.6 mg Nicotinamide: 40 mg Vitamin B6 (as Pyridoxine Hydrochloride): 4 mg Pantothenic Acid (as Dexpanthenol): 15 mg Ascorbic Acid (as Sodium Ascorbate): 100 mg Biotin: 0.06 mg Folic Acid: 0.4 mg Vitamin B12 (as Cyanocobalamin): 0.005 mg. This is a sterile, lyophilized powder of water-soluble vitamins for infusion. It contains balanced amount of all the important water soluble vitamins which act as coenzymes of vital enzymes associated with crucial physiological processes, energy metabolism, cell growth and replenishment especially in brain and nerve cells. Vitamin C acts as an antioxidant and helps in collagen formation. Intravenous administration of this combination gives prompt action.
| Trade Name | Velzyme |
| Generic | Multivitamin + 5% Dextrose |
| Type | Syrup |
| Therapeutic Class | Multi-vitamin & Multi-mineral combined preparations |
| Manufacturer | |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
This is intended as a supplement for intravenous nutrition in order to meet the daily requirements of the water soluble vitamins of NPO (nothing by mouth) or surgery patients.
Dosage
Velzyme dosage
Adults and children weighing 10 kg or more: 1 vial (10 ml) daily.
Children weighing less than 10 kg: should be given 1 ml of the dissolved mixture per kg body weight/day.
The contents of one vial are dissolved by the aseptic addition of 10 ml of one of the following:
- Water for injection
- Fat emulsion 10%
- Glucose solution for infusion (5% to 60%)
- Normal saline (0.9% Sodium Chloride)
Side Effects
Allergic reactions may occur in patients hypersensitive to any component of the preparation, e.g. Thiamine.
Precaution
When Lyophilized Powder for Infusion is diluted with water-based solutions, the admixture sould be protected from light. This is not necessary if lyophilized powder for infusion is diluted with intralipid because of the protective effect of the fat emulsion.
Interaction
Vitamin B6 can reduce the effect of Levodopa. Folic Acid may lower the serum concentration of Phenytoin.
Pregnancy & Breastfeeding use
Animal reproduction studies or clinical investigations during pregnancy have not been carried out with Multivitamin & 5% Dextrose. However, there are published reports on safe administration of water soluble vitamins in this patient group.
Contraindication
Known hypersensitivity to any of the components, e.g. Thiamine.
Acute Overdose
No adverse effects of an overdose of water soluble multivitamin have been reported, with exception of cases of extremely high parenteral doses. The possibility of hypervitaminosis A and D should be considered if lyophilized powder for infusion is dissolved in another multivitamin injection.
Storage Condition
Before reconstitution: Store at below 25°C in a dry place, protected from light. Keep out of reach of children. After reconstitution: The reconstituted preparation should be added to the infusion solution aseptically immediately before the start of the infusion & used within 24 hours.
Innovators Monograph
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