Vetscription Worm Away
Vetscription Worm Away Uses, Dosage, Side Effects, Food Interaction and all others data.
Vetscription Worm Away is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged compound. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. Vetscription Worm Away was first introduced as an anthelmintic in 1953. Vetscription Worm Away compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.
Vetscription Worm Away is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Vetscription Worm Away hydrate and piperazine citrate are the main anthelminthic piperazines.
| Trade Name | Vetscription Worm Away |
| Availability | Discontinued |
| Generic | Piperazine |
| Piperazine Other Names | Diethylenediamine, Piperazidine, Piperazin, Piperazina, Piperazine |
| Related Drugs | albendazole, mebendazole, nitazoxanide, pyrantel, Albenza, Alinia, Emverm, Ascarel |
| Type | For animal use only |
| Formula | C4H10N2 |
| Weight | Average: 86.1356 Monoisotopic: 86.08439833 |
| Protein binding | 60-70% |
| Groups | Approved, Vet approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | United States |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Vetscription Worm Away is a medication used to treat roundworm and pinworm.
Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.
Vetscription Worm Away is also used to associated treatment for these conditions: Ascaris lumbricoides infection, Enterobius vermicularis infection
How Vetscription Worm Away works
Vetscription Worm Away is a GABA receptor agonist. Piperzine binds directly and selectively to muscle membrane GABA receptors, presumably causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.
Toxicity
LD50 = 5 g/kg (Human, oral). Symptoms of overdose include muscle fatigue, seizures, and difficulty breathing.
Food Interaction
- Take with or without food. The absorption is unaffected by food.
Vetscription Worm Away Disease Interaction
Major: liver disease, renal dysfunctionModerate: supportive therapy, seizure disorders
Elimination Route
Rapidly absorbed from the gastrointestinal tract
Innovators Monograph
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