Vetscription Worm Away Uses, Dosage, Side Effects and more

Vetscription Worm Away is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged compound. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. Vetscription Worm Away was first introduced as an anthelmintic in 1953. Vetscription Worm Away compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.

Vetscription Worm Away is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Vetscription Worm Away hydrate and piperazine citrate are the main anthelminthic piperazines.

Trade Name Vetscription Worm Away
Availability Discontinued
Generic Piperazine
Piperazine Other Names Diethylenediamine, Piperazidine, Piperazin, Piperazina, Piperazine
Related Drugs albendazole, mebendazole, nitazoxanide, pyrantel, Albenza, Alinia, Emverm, Ascarel
Type For animal use only
Formula C4H10N2
Weight Average: 86.1356
Monoisotopic: 86.08439833
Protein binding

60-70%

Groups Approved, Vet approved
Therapeutic Class
Manufacturer
Available Country United States
Last Updated: January 7, 2025 at 1:49 am

Uses

Vetscription Worm Away is a medication used to treat roundworm and pinworm.

Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.

Vetscription Worm Away is also used to associated treatment for these conditions: Ascaris lumbricoides infection, Enterobius vermicularis infection

How Vetscription Worm Away works

Vetscription Worm Away is a GABA receptor agonist. Piperzine binds directly and selectively to muscle membrane GABA receptors, presumably causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.

Toxicity

LD50 = 5 g/kg (Human, oral). Symptoms of overdose include muscle fatigue, seizures, and difficulty breathing.

Food Interaction

Disease Interaction

Major: liver disease, renal dysfunctionModerate: supportive therapy, seizure disorders

Elimination Route

Rapidly absorbed from the gastrointestinal tract

Innovators Monograph

*** Taking medicines without doctor's advice can cause long-term problems.
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