Virginiamycin M1 Uses, Dosage, Side Effects and more
Pristinamycin IIA is a macrolide antibiotic, a member of the streptogramin A group of antibiotics, and one component of pristinamycin. It is produced by Streptomyces graminofaciens and other bacteria.
| Trade Name | Virginiamycin M1 |
| Generic | Virginiamycin M1 |
| Virginiamycin M1 Other Names | Mikamycin A, Ostreogrycin A, Pristinamycin IIA, Streptogramin A, Virginiamycin factor M1, Virginiamycin M1 |
| Type | |
| Formula | C28H35N3O7 |
| Weight | Average: 525.5934 Monoisotopic: 525.247500489 |
| Groups | Experimental |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
For the treatment of bacterial infections.
How Virginiamycin M1 works
Virginiamycin M1 is a macrocyclic lactone antibiotic that acts syngeristically with the structurally unrelated cyclic depsipeptides more commonly known as the virginiamycins B (ostreogrycin B or streptogramin B) and S to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Virginiamycin M1 has proven to be highly active against Gram positive bacteria, particularly methicillin-resistant S. aureus.
