Visi Blue
Visi Blue Uses, Dosage, Side Effects, Food Interaction and all others data.
Visi Blue is a selective tissue staining agent (dye) which stains anterior lens capsule of the human crystalline lens. The dye does not penetrate the capsule, permitting visualization of the anterior capsule in contrast to the non-stained lens cortex and inner lens material.
| Trade Name | Visi Blue |
| Generic | Trypan Blue |
| Weight | 06% |
| Type | Eye Drops, Ophthalmic Solution |
| Therapeutic Class | Preparations for Ophthalmic diagnosis |
| Manufacturer | Incepta Pharmaceuticals Ltd, Incepta Pharmaceuticals Limited |
| Available Country | India, Bangladesh |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Visi Blue is used for use as an aid in ophthalmic surgery by staining the anterior capsule of the lens.
Dosage
Visi Blue dosage
The first step to administer Visi Blue is to inject an air bubble into the anterior chamber using a 26 gauge needle. It prevents dilution of dye by the aqueous humor. Then Visi Blue is injected into the anterior lens capsule using a tuberculin syringe. Sufficient staining is achieved as soon as the dye has contracted the capsule. If some area is left unstained, inject one more drop till it gets stained.
Side Effects
- Discoloration of high water content hydrogen intraocular lenses.
- Inadvertent staining of the posterior lens capsule and vitreous face.
- It is generally self limited, lasting up to one week.
Precaution
It is recommended that after injection all excess Visi Blue should be immediately removed from the eye by thorough irrigation of the anterior chamber.
Pregnancy & Breastfeeding use
Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women. Visi Blue should be given to a pregnant woman only if the potential benefit justifies the potential risk to the fetus.
Lactation: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Visi Blue is administered to a nursing woman.
Contraindication
Visi Blue is contraindicated when a non-hydrated (dry state), hydrophilic acrylic intraocular lens (IOL) is planned to be inserted into the eye because the dye may be absorbed by the IOL and stain the IOL.
Special Warning
Pediatric use: The safety and effectiveness of Visi Blue have been established in pediatric patients. Use of Visi Blue is supported by evidence from an adequate and well controlled study in pediatric patients.
Geriatric use: No overall differences in safety and effectiveness have been observed between elderly and younger patients.
Storage Condition
Store below 30° C and keep away from light.
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FAQ
What is Visi Blue used for?
Visi Blue is a diazo dye that has been widely used to color dead tissues or cells selectively.The mechanism of trypan blue staining is based on it being negatively charged and not interacting with cells unless the membrane is damaged.
How safe is Visi Blue?
Visi Blue may cause cancer, genetic defects, and damage fertility, or cause harm to an unborn child.Special precautions should be taken to avoid exposing operators to trypan blue whilst working with and disposing of the dye.
What are the common side effects of Visi Blue?
Common side effects of Visi Blue include: temporary blue coloration of the eye, and staining of implanted lenses.
Is Visi Blue safe during pregnancy?
This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.
Is Visi Blue safe during breastfeeding?
It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when trypan blue is administered to a nursing woman.
How does Visi Blue work?
Visi Blue binds to intracellular proteins and render the cells a blue color.
Why is Visi Blue used in cataract surgery?
Visi Blue is the most frequently used in cataract surgery due to its safety, availability and effectiveness.
Is Visi Blue toxic to humans?
Visi Blue is not toxic, in terms of cell viability, over an exposure time of up to 60s; however, further exposure results in a gradual increase in damage of cultured human trabecular meshwork cells.
