Vitreolent

Vitreolent Uses, Dosage, Side Effects, Food Interaction and all others data.

Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperthyroidism (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.

It works in the thyroid gland. By inhibiting thyroid hormone synthesis and release, thyroid gland vascularity is reduced, thyroid gland tissue becomes firmer, thyroid cell size is reduced, follicular colloid reaccumulates, and bound iodine levels increase. As a protectant following radiation exposure, KI blocks the uptake of radioactive iodine isotopes by the thyroid gland thereby minimizing the risk of radiation-induced thyroid neoplasms.

Sodium iodide is a water-soluble ionic compound with a crystal lattice. Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition but is more commonly used in veterinary medicine. Radiolabelled compound, Iodide I-131, is used as a diagnostic tool to evaluate thyroid function and morphology.

When intravenously administered for total parental nutrition, sodium iodide prevents the depletion of endogenous stores of iodine and subsequent deficiency symptoms .

Vitreolent
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Vitreolent
Generic	Potassium Iodide + Sodium Iodide
Weight	0.3%w/v,
Type	Eye Drops
Therapeutic Class
Manufacturer	Novartis Pharma (pak) Ltd, Omnivision
Available Country	Pakistan, Switzerland
Last Updated:	September 19, 2023 at 7:00 am

Uses

Potassium Iodide is an oral antithyroid agent used for the prevention of radioactive iodine uptake into the thyroid gland during a nuclear radiation emergency.

Potassium Iodide is oral antithyroid agent used in the prevention of radioactive iodine uptake into the thyroid gland during a nuclear radiation emergency. Potassium Iodide may be used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution.

Sodium iodide is a supplement used in total parenteral nutrition.

Indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN) .

Vitreolent is also used to associated treatment for these conditions: Acute radiation sickness, Folate deficiency, Goitre, Hypothyroidism, Iodine Deficiency, Iron Deficiency (ID), Thyroid Cancers, Nutritional supplementation, Skin disinfection, Oral disinfectionAbscesses, Bleeding of the Vitreal Body, Clouding of the Lenses, Vitreous opacities, Wounds, Total parenteral nutrition therapy

Toxicity

Acute oral LD50 is 4340 mg/kg in rat and 1000 mg/kg in mouse . Chronic iodide overdoses may result in iodism, which is commonly characterized by salivation, coryza, sneezing, conjunctivitis, headache, fever, laryngitis, bronchitis, stomatitis, parotitis and oedema of the glottis . Up to 10g of sodium iodide has been administered intravenously without any signs of toxicity .