Viviq

Viviq Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name Viviq
Generic Propentofylline
Propentofylline Other Names Propentofylline
Type
Formula C15H22N4O3
Weight Average: 306.3602
Monoisotopic: 306.16919059
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Viviq
Viviq

Uses

Investigated for use/treatment in alzheimer's disease.

How Viviq works

Viviq is a xanthine derivative and phosphodiesterase inhibitor with purported neuroprotective effects. It inhibits both phosphodiesterase and adenosine uptake. Phosphodiesterase has shown to associated with age-related memory impairment and Alzheimer's disease. β-Amyloid protein 1–42 (β42) can induce apoptosis in the cultured hippocampal neurons, suggesting that it plays an important role in causing neurodegeneration in Alzheimer's disease. Viviq is also capable of activating a cAMP–PKA system, depressing the caspase cascade and modifying Bcl-2 family proteins. Viviq blocked both the apoptotic features induced by β42 and further induced an anti-apoptotic protein, Bcl-2. It suggests that the protection of propentofylline on the β42-induced neurotoxicity is caused by enhancing anti-apoptotic action through cAMP–PKA system.

Innovators Monograph

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