Weinsteinsäure
Weinsteinsäure Uses, Dosage, Side Effects, Food Interaction and all others data.
Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.
Tartaric acid is used to generate carbon dioxide through interaction with sodium bicarbonate following oral administration. Carbon dioxide extends the stomach and provides a negative contrast medium during double contrast radiography. In high doses, this agent acts as a muscle toxin by inhibiting the production of malic acid, which could cause paralysis and maybe death.
Trade Name | Weinsteinsäure |
Generic | L-tartaric acid |
L-tartaric acid Other Names | ácido tartárico, L-threaric acid, Rechtsweinsäure, Tartaric acid, Weinsteinsäure |
Type | |
Formula | C4H6O6 |
Weight | Average: 150.0868 Monoisotopic: 150.016437924 |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Tartaric Acid is primarily indicated in conditions like Antiscorbutic, Antiseptic.
Weinsteinsäure is also used to associated treatment for these conditions: Acid indigestion, Dysuria, Heartburn, Kidney Stones, Pain, Upset stomach
Toxicity
Routes of Entry: Inhalation. Ingestion.
Toxicity to Animals: Lowest Published Lethal Dose: LDL [Rat - Route: oral; Dose: 7500 mg/kg LDL Rabbit - Route: Oral; Dose: 5000 mg/kg LDL [Dog] - Rout: Oral; Dose: 5000 mg/kg Lethal Dose/Conc 50% kill: LD50 [Mouse] - Route: Intravenous; Dose: 485 mg/kg
Other Toxic Effects on Humans: Acute Potential Health Effects: Skin: Causes skin irritation Eyes: Causes eye irritation Inhalation: Causes respiratory tract irritation Ingestion: Causes gastrointestinal tract irritation with nausea, vomiting and diarrhea. May affect kidneys (kidney damage), blood, and behavior (convulsions, somnolence), and respiration. Chronic Potential Health Effects: Ingestion: Repeated or prolonged ingestion may cause lesions of the mouth, gastric ulcers, gastrointestinal hyperacidity, and symptoms similar to those of metal fume fever - flu-like condition with fever, chills, sweats, nausea, vomiting, muscle aches, pains, and weakness. Skin: Repeated or prolonged skin contact may cause skin ulcerations or lesions.
Elimination Route
Oral or parenteral doses of monosodium 14C-L(+)-tartrate (400 mg/kg) are rapidly excreted by rats and a proportion completely metabolized to CO2. The oral dose was well-absorbed.
Elimination Route
Only about 15-20% of consumed tartaric acid is secreted in the urine unchanged.
Innovators Monograph
You find simplified version here Weinsteinsäure