Winkavit
Winkavit Uses, Dosage, Side Effects, Food Interaction and all others data.
Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Insures the adequate absorption of calcium; helps form collagen ( which makes up bone cartilage & connective tissues); aids in the production of antibodies, hormones & enzymes. Recent studies have shown that Lysine may be effective against herpes by improving the balance of nutrients that reduce viral growth. A deficiency may result in tiredness, inability to concentrate, irritability, bloodshot eyes, retarded growth, hair loss, anemia & reproductive problems.
Vitamin-B complex contains the most important members of the vitamin B group in pure form and in therapeutically balanced proportions. The members of the vitamin B group contained in Vitamin-B complex are components of enzyme systems that regulate various stages of carbohydrate, fat and protein metabolism, each of the components playing a specific biological role. Deficiency of B vitamin causes glossitis, stomatitis, cheilosis, polyneuritis, beriberi, pellagra and vascularisation of cornea.
| Trade Name | Winkavit |
| Generic | Lysine + Vitamin B Complex |
| Type | Syrup |
| Therapeutic Class | |
| Manufacturer | Zanctok Pharmaceuticals |
| Available Country | Pakistan |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Lysine is an amino acid commonly found as a component of total parenteral nutrition.
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Each Tablet/ Capsule contains:
- Thiamine Hydrochloride 5 mg
- Riboflavin 2 mg
- Pyridoxine hydrochloride 2 mg
- Nicotinamide 20 mg
Each 5 ml Syrup contains:
- Thiamine Hydrochloride 5 mg
- Riboflavin 2 mg
- Pyridoxine hydrochloride 2 mg
- Nicotinamide 20 mg
Each 2 ml Injection contains:
- Thiamine Hydrochloride 50 mg
- Riboflavin 4 mg
- Pyridoxine hydrochloride 10 mg
- Nicotinamide 100 mg
- D-Panthenol 5 mg
Vitamin-B complex is used for prophylactic or therapeutic nutritional supplementation in physiologically stressful conditions. These include: Conditions causing depletion, or reduced absorption or bioavailability of essential B-vitamins manifested by glossitis, stomatitis, cheilosis, beriberi Vitamin-B complex is used for prophylactic or therapeutic nutritional supplementation in physiologically stressful conditions. These include: Conditions causing depletion, or reduced absorption or bioavailability of essential B-vitamins manifested by glossitis, stomatitis, cheilosis, beriberi
Winkavit is also used to associated treatment for these conditions: Weight Loss, Weight Gain, Amino acid supplementation
How Winkavit works
Proteins of the herpes simplex virus are rich in L-arginine, and tissue culture studies indicate an enhancing effect on viral replication when the amino acid ratio of L-arginine to lysine is high in the tissue culture media. When the ratio of L-lysine to L-arginine is high, viral replication and the cytopathogenicity of herpes simplex virus have been found to be inhibited. L-lysine may facilitate the absorption of calcium from the small intestine.
Dosage
Winkavit dosage
Tablet/ capsule:usual recommended dose is 1-2 tablet/capsule 3 times daily or as directed by the physician.
Syrup:2-3 teaspoonful daily or as directed by the physician.
Injection:It is for intramuscular and intravenous administration. Usual recommended dose is 2 ml daily or as directed by the physician. In addition withThiamine, Riboflavin, Nicotinamide, Pyridoxine; injectable dosage from containsD-Panthenol 5 mg.
Side Effects
Adverse reactions have been reported with specific vitamins and minerals, but generally at levels substantially higher than those in Vitamin-B complex. However, allergic and idiosyncratic reactions are possible at lower levels. Iron, even at the usual recommended level has been associated with gastrointestinal intolerance in some patients.
Interaction
As little as 5 mg pyridoxine daily can decrease the efficacy of levodopa in the treatment of parkinsonism. Therefore, Vitamin-B complex is not recommended for patients undergoing such therapy
Elimination Route
Absorbed from the lumen of the small intestine into the enterocytes by an active transport process
Pregnancy & Breastfeeding use
It is safe to use Vitamin-B complex in pregnancy and lactation.
Contraindication
Vitamin-B complex is contraindicated in patients hypersensitive to any of its components.
Innovators Monograph
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