WX-UK1

WX-UK1 Uses, Dosage, Side Effects, Food Interaction and all others data.

WX-UK1 is a 3-amidinophenylalanine-based non-cytotoxic small molecule that belongs to a new class of drugs. In animal models, WX-UK1 blocks tumor cell invasion, metastasis and primary tumor growth by inhibiting serine proteases and the urokinase Plasminogen Activator (uPA) system, which have been shown to play a key role in metastasis and primary tumor growth of breast, gastric, colon cancer, and various other solid tumors. Independent studies show that administration of Wx-UK1 resulted in a decrease of tumor cell invasion, suggesting its efficacy as a an adjuvant antimetastatic therapy of carcinomas.

WX-UK1 is a 3-amidinophenylalanine-based non-cytotoxic small molecule that belongs to a new class of drugs. In animal models, WX-UK1 blocks tumor cell invasion, metastasis and primary tumor growth by inhibiting serine proteases and the urokinase Plasminogen Activator (uPA) system, which have been shown to play a key role in metastasis and primary tumor growth of breast, gastric, colon cancer, and various other solid tumors.

Trade Name WX-UK1
Generic WX-UK1
Type
Formula C32H48ClN5O5S
Weight Average: 650.28
Monoisotopic: 649.3064685
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
WX-UK1
WX-UK1

Uses

Investigated for use/treatment in solid tumors.

How WX-UK1 works

Activity at urokinase plasminogen activator receptors (uPAR) results in inhibition of uPA system.

Innovators Monograph

You find simplified version here WX-UK1

*** Taking medicines without doctor's advice can cause long-term problems.
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