You Bi Da
You Bi Da Uses, Dosage, Side Effects, Food Interaction and all others data.
You Bi Da is a spasmolytic flavone derivative that acts by relaxing the smooth muscle in the urinary tract. You Bi Da is a competitive muscarinic receptor antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Muscarinic receptors play an important role in several major cholin-ergically mediated functions, including contractions of urinary bladder smooth muscle and stimulation of salivary secretion.
You Bi Da acts as a direct antagonist at muscarinic acetylcholine receptors in cholinergically innervated organs. Its anticholinergic-parasympatholytic action reduces the tonus of smooth muscle in the bladder, effectively reducing the number of required voids, urge incontinence episodes, urge severity and improving retention, facilitating increased volume per void.
Trade Name | You Bi Da |
Availability | Prescription only |
Generic | Flavoxate |
Flavoxate Other Names | Flavoxate, Flavoxato, Flavoxatum |
Related Drugs | oxybutynin, Myrbetriq, phenazopyridine, Pyridium, solifenacin, tolterodine, mirabegron, Ditropan, Detrol, VESIcare |
Type | |
Formula | C24H25NO4 |
Weight | Average: 391.4596 Monoisotopic: 391.178358293 |
Groups | Approved |
Therapeutic Class | BPH/ Urinary retention/ Urinary incontinence |
Manufacturer | |
Available Country | China |
Last Updated: | September 19, 2023 at 7:00 am |
![You Bi Da You Bi Da](https://www.medicinesfaq.com/media/png/you-bi-da.png)
Uses
You Bi Da is used for symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis and urethrocystitis.
You Bi Da is also used to associated treatment for these conditions: Cystitis, Dysuria, Kidney Stones, Menstrual Distress (Dysmenorrhea), Neurogenic Bladder Dysfunction, Nocturia, Pelvic Floor Dysfunctions, Pelvic Pain, Prostatitis, Suprapubic pain, Urethritis, Urethrotrigonitis, Urinary Incontinence (UI), Urinary Tract Infection, Urinary Urgency, Uterine dyskinesia, Cystalgia, Urethrocystitis
How You Bi Da works
You Bi Da acts as a direct antagonist at muscarinic acetylcholine receptors in cholinergically innervated organs. Its anticholinergic-parasympatholytic action reduces the tonus of smooth muscle in the bladder, effectively reducing the number of required voids, urge incontinence episodes, urge severity and improving retention, facilitating increased volume per void.
Dosage
You Bi Da dosage
Adults and children over 12 years of age: 100 mg to 200 mg 3 times a day. With improvement of symptoms, the dose may be reduced.
Pediatric Use: Safety and effectiveness in children below the age of 12 years have not been established.
Side Effects
Gastrointestinal: Nausea, vomiting, dry mouth.
CNS: Vertigo, headache, mental confusion, especially in the elderly, drowsiness, nervousness.
Hematologic: Leukopenia (which is reversible upon discontinuation of the drug).
Cardiovascular: Tachycardia and palpitation.
Allergic: Urticaria and other dermatoses, eosinophilia and hyperpyrexia.
Ophthalmic: Increased ocular tension, blurred vision, disturbance in eye accommodation.
Toxicity
The oral LD50 for flavoxate HCl in rats is 4273 mg/kg. The oral LD50 for flavoxate HCl in mice is 1837 mg/kg. Symptoms of overdose include convulsions, decreased ability to sweat, (warm, red skin, dry mouth, and increased body temperature), hallucinations, increased heart rate and blood pressure, and mental confusion.
Precaution
You Bi Da should be given cautiously in patients with suspected glaucoma
Food Interaction
- Take with or without food. The absorption is unaffected by food.
[Moderate] GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents.
Use in combination may result in additive central nervous system depression and
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol.
Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
You Bi Da Drug Interaction
Moderate: tramadol, tramadolMinor: acetaminophen, acetaminophen, acetaminophen, acetaminophenUnknown: ginkgo, ginkgo, phenazopyridine, phenazopyridine, levothyroxine, levothyroxine, cyanocobalamin, cyanocobalamin, ascorbic acid, ascorbic acid, ergocalciferol, ergocalciferol, cholecalciferol, cholecalciferol
You Bi Da Disease Interaction
Major: GI/urinary obstructionModerate: angle-closure glaucoma
Elimination Route
Well absorbed from gastrointestinal tract.
Elimination Route
57% of the flavoxate HCl was excreted in the urine within 24 hours.
Pregnancy & Breastfeeding use
Pregnancy: Pregnancy Category B. This drug should be used during pregnancy only if clearly needed.
Nursing Mothers: It is not known whether this drug is excreted in human milk. Caution should be exercised when flavoxate is administered to a nursing woman.
Contraindication
You Bi Da is contraindicated in patients who have any of the following obstructive conditions: pyloric or duodenal obstruction, obstructive intestinal lesions or ileus, achalasia, gastrointestinal hemorrhage and obstructive uropathies of the lower urinary tract.
Storage Condition
Store You Bi Da at room temperature, between 20 and 25 degrees C
Innovators Monograph
You find simplified version here You Bi Da
You Bi Da contains Flavoxate see full prescribing information from innovator You Bi Da Monograph, You Bi Da MSDS, You Bi Da FDA label