Z-HYALIN plus
Z-HYALIN plus Uses, Dosage, Side Effects, Food Interaction and all others data.
Sodium hyaluronate is a polysaccharide which functions as a tissue lubricant. It is widely used in ophthalmic surgery because it forms a viscoelastic solution in water which makes it a suitable substitute for aqueous and vitreous humour.
| Trade Name | Z-HYALIN plus |
| Generic | Sodium Hyaluronate |
| Type | |
| Therapeutic Class | Drugs for Osteoarthritis |
| Manufacturer | |
| Available Country | Germany |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Z-HYALIN plus is used for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy, and to simple analgesics, e.g., acetaminophen.
Z-HYALIN plus is a viscous solution consisting of a high molecular weight fraction of purified natural sodium hyaluronate in buffered physiological sodium phosphate. It has a pH of 5.5-7.0. Hyaluronic acid is an important component of the body's extracellular matrix and is present in a particularly high concentration in cartilage and synovial fluid. Endogenous hyaluronic acid provides viscosity and elasticity to synovial fluid, which is fundamental for its lubricating and shock absorbing properties. It is essential for the correct structure of proteoglycans in articular cartilage. In osteoarthritis there is an insufficient amount of and a chance in the quality of hyaluronic acid in synovial fluid and cartilage. The intra-articular administration of hyaluronic acid into arthritic joints with degenerating cartilage surfaces and pathologically altered synovial fluid improved functions.
Dosage
Z-HYALIN plus dosage
Z-HYALIN plus is administered by intra-articular injection. A treatment cycle consists of five injections given at weekly intervals. Some patients may experience benefit with three injections given at weekly intervals. Inject the full 2 ml in one knee only. If treatment is bilateral, a separate injection should be used for each knee.
Side Effects
The common side-effects include gastrointestinal complaints, injection site pain, knee swelling/effusion, local skin reactions (rash, ecchymosis), pruritus, and headache.
Precaution
Use caution when injecting Z-HYALIN plus into patients who are allergic to avian proteins, feathers, and egg products. Strict aseptic administration technique must be followed. Remove joint effusion, if present, before injecting Z-HYALIN plus. Do not use the same syringe for removing joint effusion and for injecting Z-HYALIN plus. It is recommended that the patient avoid any strenuous activities or prolonged (i.e., more than 1 hour) weight-bearing activities such as jogging or tennis within 48 hours following the intra-articular injection.
Pregnancy & Breastfeeding use
The safety and effectiveness of Z-HYALIN plus have not been established in pregnant women. It is not known if Z-HYALIN plus is excreted in human milk. The safety and effectiveness of Z-HYALIN plus have not been established in lactating mother. The safety and effectiveness of Z-HYALIN plus have not been demonstrated in children.
Contraindication
The drug is contraindicated in patients with known hypersensitivity to hyaluronate preparations. Intra-articular injections are contraindicated in cases of past and present infections or skin diseases in the area of the injection site.
Acute Overdose
No case of over dosage has been reported to date.
Storage Condition
Hyronate injection should be stored in a cool (below 25° C) and dry place and protected from light. Protect from freezing.
Innovators Monograph
You find simplified version here Z-HYALIN plus
FAQ
What is Z-HYALIN plus used for?
Z-HYALIN plus topical skin medication is used to treat skin ulcers such as bed sores or diabetic foot ulcers, as well as burn wounds, surgical incisions, cuts, abrasions, and other skin irritations. Z-HYALIN plus skin medication is also used to treat dry or scaly skin.
How safe is Z-HYALIN plus?
Z-HYALIN plus as well as are considered safe. It's rarely associated with side effects when applied topically.
How does Z-HYALIN plus work?
Z-HYALIN plus works by pulling in moisture from the environment and the underlying layers of your skin into the epidermis.
What are the common side effects of Z-HYALIN plus?
The common side effects of Z-HYALIN plus are include:
- warmth, pain, redness, stiffness, bruising, or puffiness where the medicine was injected;
- nausea, stomach pain;
- trouble walking;
- swelling in your hands or feet;
- back pain, joint pain, muscle pain;
- numbness or tingly feeling;
- headache, dizziness; or
- runny or stuffy nose, sneezing, sore throat.
How is Z-HYALIN plus given?
Z-HYALIN plus is injected directly into your knee joint. A healthcare provider will give you this injection.
Z-HYALIN plus is usually given once every week for 3 to 5 weeks. Follow your doctor's dosing instructions very carefully.
Who should not take Z-HYALIN plus?
You should not receive a Z-HYALIN plus injection if you have an infection in your knee or in the skin around your knee.
Is Z-HYALIN plus safe during pregnancy?
Z-HYALIN plus also safe to use during pregnant.
Is Z-HYALIN plus safe during breastfeeding?
It is not known whether Z-HYALIN plus topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Is Z-HYALIN plus safe for skin?
Z-HYALIN plus are considered safe. It's rarely associated with side effects when applied topically.
How long take Z-HYALIN plus?
Z-HYALIN plus usually given once every week for 3 to 5 weeks.
How long does Z-HYALIN plus last?
Z-HYALIN plus lasts for about six months or longer in most people.
How much Z-HYALIN plus should I take?
Doses of 120–240 mg per day for at least one month have been shown to significantly increase skin moisture and reduce dry skin in adults.
Does Z-HYALIN plus have long term benefits?
Studies show that long term use is safe, with no reported side effects from Z-HYALIN plus supplementation. Used as a topical skincare ingredient, Z-HYALIN plus is also well tolerated.
Is it OK to use Z-HYALIN plus every day?
Yes, you can even use it twice a day as long as you're applying it to clean, damp skin, then locking it in with a moisturizer and face oil.
What happens if you use too much Z-HYALIN plus?
Too much Z-HYALIN plus can leave skin thirstier, and dehydration lines more prominent.
Does Z-HYALIN plus lighten dark spots?
Z-HYALIN plus can also minimize age spots and prevent any dark spots in the future on your skin.
Can Z-HYALIN plus dry skin?
Z-HYALIN plus is one of the most hydrating ingredients, but if misused,Z-HYALIN plus can actually dry out your skin.
Is Z-HYALIN plus good for pimples?
While Z-HYALIN plus can't fill in visible acne scars, it can help reduce redness and the visible appearance of acne.
Is Z-HYALIN plus good for wrinkles?
Z-HYALIN plus is well known for its skin benefits, especially alleviating dry skin, reducing the appearance of fine lines and wrinkles and speeding up wound healing.
Is Z-HYALIN plus good for hair?
You can use Z-HYALIN plus regardless of your hair type. It'll help your hair follicles lock in moisture.
Can I use Z-HYALIN plus under eyes?
Yes you can.Z-HYALIN plus can help mask darkness under the eyes.
What does Z-HYALIN plus do to your face?
Z-HYALIN plus helps reduce the visibility of fine lines and wrinkles retaining moisture to the skin.
Can Z-HYALIN plus cause facial hair growth?
Z-HYALIN plus is similar to a fertilizer because it can increase hair growth.
What happen If I missed Z-HYALIN plus?
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
What happens if I overdose?
Z-HYALIN plus may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing.call a poison control center right away.
