Zirgan Ophthalmic Gel 0.15%
Zirgan Ophthalmic Gel 0.15% Uses, Dosage, Side Effects, Food Interaction and all others data.
| Trade Name | Zirgan Ophthalmic Gel 0.15% |
| Generic | Ganciclovir (Ophthalmic) |
| Weight | 0.15% |
| Type | Ophthalmic Gel |
| Therapeutic Class | Ophthalmic Anti-viral Products |
| Manufacturer | Ibn Sina Pharmaceuticals Ltd. |
| Available Country | Bangladesh |
| Last Updated: | October 19, 2023 at 6:27 am |
Uses
It is a topical eye antiviral that is indicated for the treatment of acute herpetic keratitis (dendritic ulcers)Dosage
Zirgan Ophthalmic Gel 0.15% dosage
The recommended dosing regimen for Ganciclovir eye gel 0.15% is 1 drop in the affected eye 5 times per day (approximately every 3 hours while awake) until the corneal ulcer heals and then 1 drop 3 times per day for 7 days.Side Effects
Most common adverse reactions reported in patients were blurred vision (60%), eye irritation (20%), punctate keratitis (5%), and conjunctival hyperemia (5%).Precaution
It is indicated for topical eye use only. Patients should not wear contact lenses if they have signs or symptoms of herpetic keratitis or during the course of therapy with it.Pregnancy & Breastfeeding use
Pregnancy Category C. Ganciclovir has been shown to be embryo toxic in rabbits and mice following intravenous administration and teratogenic in rabbits. Fetal resorptions were present in at least 85% of rabbits and mice administered 60 mg/kg/day and 108 mg/kg/day (approximately 10,000x and 17,000x the human ocular dose of 6.25 mcg/kg/day), respectively, assuming complete absorption.Nursing Mothers: It is not known whether topical eye ganciclovir administration could result in sufficient systemic absorption to produce detectable quantities in breast milk. Caution should be exercised when it is administered to nursing mothers.Contraindication
It is contraindicated to the patients with known hypersensitivity to Ganciclovir.Special Warning
Pediatric Use: Safety and efficacy in pediatric patients below the age of 2 years have not been established.Geriatric Use: No overall differences in safety or effectiveness have been observed between elderly and younger patients.Acute Overdose
Overdose through local or accidental oral administration is not likely.Storage Condition
Store at 15°C to 30°C in a dry place protected from light. It is desirable that the contents should not be used more than one month after first opening of the tube.Innovators Monograph
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