Zofther

Zofther Uses, Dosage, Side Effects, Food Interaction and all others data.

Zofther, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases.

Trade Name Zofther
Generic Artemotil
Artemotil Other Names Arteether, Artemotil, beta-Arteether, beta-Dihydroartemisinin ethyl ether, Dihydroartemisinin ethyl ether
Type Injection
Formula C17H28O5
Weight Average: 312.406
Monoisotopic: 312.193674002
Groups Approved
Therapeutic Class
Manufacturer Elder Pharmaceuticals Ltd
Available Country India
Last Updated: September 19, 2023 at 7:00 am
Zofther
Zofther

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FAQ

What is Zofther used for?

Zofther is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases. It is a semi-synthetic derivative of artemisinin, a natural product of the Chinese plant Artemisia annua.

How safe is Zofther?

A meta-analysis confirmed that Zofther are potent, effective, and safe in patients with uncomplicated malaria compared with other antimalarial agents.

What are the common side effects of Zofther?

Common side effects of Zofther are include:

  • Headache
  • Nausea or Vomiting
  • Persistent cough
  • Dizziness
  • Body pain
  • Pain at the injection site
  • Stomach discomfort and pain
  • Chills and rigor
  • Watery diarrhea
  • Unusual tiredness and weakness
  • Low WBC and Platelet count
  • Swelling of the liver

Is Zofther safe during pregnancy?

The World Health Organization currently advises against the use of Zofther in the first trimester of pregnancy, unless in a lifesaving situation where other drugs are not suitable. In the second and third trimesters of pregnancy, Zofther and its derivatives are not recommended unless alternative drug treatments are unsuitable.

Is Zofther safe during breastfeeding?

It is recommended that you do not breastfeed while taking Zofther, as it is not known whether Zofther passes into breast milk.

Can I drink alcohol with Zofther?

Zofther and alcohol together has not been proven to cause harm, therefore it is safe to drink while taking your Zofther. However, as always, it is best to consume alcohol within the recommended guidelines to stay safe and look after your health.

How much Zofther can I take daily?

The recommended dose schedule is 3.2 mg beta-arteether/kg body weight on day 1, followed by 1.6 mg beta-arteether/kg on days 2 through 5.

Who should not take Zofther?

Use of Zofther should be avoided in patients who are allergic to Zofther or any of its components. However, if you are not aware of any allergy or if you are usingZofther for the first time, consult your doctor.

What are the common side effects of Zofther?

Cardiac effects such as bradycardia and QT interval prolongation. Pain at the injection site. This can be overcome by administering repeated injections in alternate thighs.

How safe is Zofther?

Zofther is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

How should Zofther administered ?

Zofther should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention.



*** Taking medicines without doctor's advice can cause long-term problems.
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