Zymarin Ophthalmic Solution 0.5%
Zymarin Ophthalmic Solution 0.5% Uses, Dosage, Side Effects, Food Interaction and all others data.
| Trade Name | Zymarin Ophthalmic Solution 0.5% |
| Generic | Gatifloxacin (Ophthalmic) |
| Weight | 0.5% |
| Type | Ophthalmic Solution |
| Therapeutic Class | Ophthalmic antibacterial drugs |
| Manufacturer | Eskayef Pharmaceuticals Ltd. |
| Available Country | Bangladesh |
| Last Updated: | October 19, 2023 at 6:27 am |
Uses
Gatifloxacin eye drops is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms: Aerobic Gram-Positive Bacteria: Corynebacterium propinquum, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mitis, Streptococcus pneumoniae Aerobic Gram-Negative Bacteria: Haemophilus influenzae.Dosage
Zymarin Ophthalmic Solution 0.5% dosage
0.3% eye drops- The recommended dosage regimen for the treatment of bacterial conjunctivitis is: Days 1 and 2: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times daily. Days 3 through 7: Instill one drop up to 4 times daily while awake. 0.5% eye drops- Patients 1 year of age or older: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times on Day 1. Instill one drop two to four times daily in the affected eye(s) while awake on Days 2 through 7.Side Effects
The most frequently reported adverse events in the overall study population were conjunctival irritation, increased lacrimation etc.Precaution
Patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis. Avoid contaminating the applicator tip with material from the eye, fingers or other source.Interaction
Specific drug interaction studies have not been conducted with gatifloxacin eye drops. However, the systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, and enhance the effects of the oral anticoagulant warfarin and its derivatives, and has been associated with transient elevations in serum creatinine in patients receiving systemic cyclosporine concomitantly.Pregnancy & Breastfeeding use
Pregnancy Category C. Because there are no adequate and well-controlled studies in pregnant women, Gatifloxacin 0.3% eye drops should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Lactation: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Gatifloxacin is administered to a nursing woman.Contraindication
Gatifloxacin eye drops is contraindicated in patients with a history of hypersensitivity to Gatifloxacin, to other quinolones, or to any of the components in this medication. Gatiflox 0.3% eye drops should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye.Special Warning
Geriatric Use: No overall differences in safety or effectiveness have been observed between elderly and younger patients.Acute Overdose
An overdose of this medication is unlikely to threaten life.Storage Condition
Store in a cool and dry place, away from light. Keep out of reach of children.Innovators Monograph
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