10-Dehydroepothilone D

10-Dehydroepothilone D Uses, Dosage, Side Effects, Food Interaction and all others data.

10-Dehydroepothilone D is a second-generation epothilone. Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity in taxane-resistant tumors. 10-Dehydroepothilone D is a second-generation compound with increased potency, favorable tissue distribution, and ease of formulation.

Table Of contents

• 10-Dehydroepothilone D
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	10-Dehydroepothilone D
Generic	KOS-1584
KOS-1584 Other Names	(E)-9,10-Dehydroepothilone D, (E)-9,10-Didehydroepothilone D
Type
Formula	C27H39NO5S
Weight	Average: 489.67 Monoisotopic: 489.254894534
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Investigated for use/treatment in solid tumors.

How 10-Dehydroepothilone D works

Epothilones are highly potent microtubulin stabilizing compounds with a similar mechanism of action to taxanes and broad applicability in a wide range of tumors. Epothilones are active in both taxane-sensitive and taxane-resistant cancers and have demonstrated low susceptibility to tumor resistance mechanisms.

Innovators Monograph

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