10-Dehydroepothilone D Uses, Dosage, Side Effects and more
10-Dehydroepothilone D is a second-generation epothilone. Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity in taxane-resistant tumors. 10-Dehydroepothilone D is a second-generation compound with increased potency, favorable tissue distribution, and ease of formulation.
| Attribute | Details |
|---|---|
| Trade Name | 10-Dehydroepothilone D |
| Generic | KOS-1584 |
| KOS-1584 Other Names | (E)-9,10-Dehydroepothilone D, (E)-9,10-Didehydroepothilone D |
| Type | |
| Formula | C27H39NO5S |
| Weight | Average: 489.67 Monoisotopic: 489.254894534 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in solid tumors.
How 10-Dehydroepothilone D works
Epothilones are highly potent microtubulin stabilizing compounds with a similar mechanism of action to taxanes and broad applicability in a wide range of tumors. Epothilones are active in both taxane-sensitive and taxane-resistant cancers and have demonstrated low susceptibility to tumor resistance mechanisms.
