KOS-1584
KOS-1584 Uses, Dosage, Side Effects, Food Interaction and all others data.
KOS-1584 is a second-generation epothilone. Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity in taxane-resistant tumors. KOS-1584 is a second-generation compound with increased potency, favorable tissue distribution, and ease of formulation.
Trade Name | KOS-1584 |
Generic | KOS-1584 |
KOS-1584 Other Names | (E)-9,10-Dehydroepothilone D, (E)-9,10-Didehydroepothilone D |
Type | |
Formula | C27H39NO5S |
Weight | Average: 489.67 Monoisotopic: 489.254894534 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in solid tumors.
How KOS-1584 works
Epothilones are highly potent microtubulin stabilizing compounds with a similar mechanism of action to taxanes and broad applicability in a wide range of tumors. Epothilones are active in both taxane-sensitive and taxane-resistant cancers and have demonstrated low susceptibility to tumor resistance mechanisms.
Innovators Monograph
You find simplified version here KOS-1584