123I−

123I− Uses, Dosage, Side Effects, Food Interaction and all others data.

123I− (as sodium 123I−) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid gland. After incorporation, a gamma camera is used to detect the decay by electron capture to tellurium-123.

Iodine is commonly used in thyroid function diagnostic tests as this gland normally absorbs iodine through the diet for formation of the thyroid hormones triiodothyronine (T3) and its prohormone, thyroxine (T4). Radioactive I-123 in particular is effective for this use as its half-life of approximately 13.13 h (hours) is ideal for the 24-h (hour) iodine uptake test and it has a reduced radiation burden as compared to I-131.

Table Of contents

• 123I−
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	123I−
Generic	Iodide I-123
Iodide I-123 Other Names	123I−, I 123, I-123, Iodine 123, Iodine-123
Type
Formula	I
Weight	Average: 122.9061 Monoisotopic: 122.906146524
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

123I− is a radiopharmaceutical diagnostic agent used for the evaluation of the thyroid function and/or morphology.

Administration of Sodium Iodide I 123 Capsules is indicated as a diagnostic procedure to be used in evaluating thyroid function and/or morphology.

123I− is also used to associated treatment for these conditions: Metastatic Medullary Thyroid Cancer

How 123I− works

Sodium 123I− is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid gland. After incorporation, a gamma camera is used to detect the decay by electron capture to tellurium-123. Iodine is commonly used in thyroid function diagnostic tests as this gland normally absorbs iodine through the diet for formation of the thyroid hormones triiodothyronine (T3) and its prohormone, thyroxine (T4).

Food Interaction

• Limit iodine intake. Consume a low iodine diet for two weeks before the administration of 123I−.
• Take on an empty stomach. Fasting before the use of I-123 for imaging of the thyroid may increase accuracy.

Half Life

Iodine-123 decays by electron capture with a physical half-life of 13.2 hours

Innovators Monograph

You find simplified version here 123I−