2-diamine
2-diamine Uses, Dosage, Side Effects, Food Interaction and all others data.
2-diamine is an organic compound that is used as a building block for the production of many other chemical products. It is also used as an excipient in many pharmacological preparations such as creams. Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions . Sensitivity to ethylenediamine may be identified with a clinical patch test.
Trade Name | 2-diamine |
Generic | Ethylenediamine |
Ethylenediamine Other Names | 1,2-diaminoethane, Aethaldiamin, edamine, ethane-1,2-diamine, Ethyleendiamine, Ethylendiamine, Ethylene-diamine, Ethylenediamine |
Type | |
Formula | C2H8N2 |
Weight | Average: 60.0983 Monoisotopic: 60.068748266 |
Groups | Approved, Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
2-diamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.
Volume of Distribution
Vd = 0.133 l/kg
Elimination Route
After oral administration its bioavailability is about 0.34, due to a substantial first-pass effect.
Half Life
2-diamine has a short half life of ~0.55 hours .
Elimination Route
Renal excretion of the unchanged substance amounts to only about 18% after intravenous and 3% after oral administration.
Innovators Monograph
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