Amrisol

Amrisol Uses, Dosage, Side Effects, Food Interaction and all others data.

Amrisol (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.

Amrisol is a positive inotropic cardiotonic with vasodilator properties, phosphodiesterase inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.

Trade Name Amrisol
Generic Amrinone
Amrinone Other Names Amrinona, Amrinone, Amrinonum, Inamrinone
Type Injection
Formula C10H9N3O
Weight Average: 187.198
Monoisotopic: 187.074561925
Protein binding

10 to 49%

Groups Approved
Therapeutic Class
Manufacturer Ferring Pharmaceuticals Pvt Ltd
Available Country India
Last Updated: September 19, 2023 at 7:00 am
Amrisol
Amrisol

Uses

Amrisol is a positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure.

Used in the treatment of congestive heart failure.

How Amrisol works

Amrisol is a phosphodiesterase inhibitor (PDE3), resulting in increased cAMP and cGMP which leads to an increase in the calcium influx like that caused by beta-agonists resulting in increased inotropic effect.

Volume of Distribution

  • 1.2 L/kg [normal volunteers]

Half Life

5 to 8 hours

Elimination Route

The primary route of excretion in man is via the urine as both inamrinone and several metabolites (N-glycolyl, N-acetate, O-glucuronide and N-glucuronide).

Innovators Monograph

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*** Taking medicines without doctor's advice can cause long-term problems.
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