Annamycin Uses, Dosage, Side Effects and more
| Trade Name | Annamycin |
| Generic | Annamycin |
| Type | |
| Formula | C26H25IO11 |
| Weight | Average: 640.379 Monoisotopic: 640.04416 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in breast cancer and leukemia (unspecified).
How Annamycin works
Annamycin belongs to the anthracycline class of drugs, and has a pleiotropic mechanism of action where it targets topoisomerase II, causing strand breaks in DNA. Annamycin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.
