Anthelcide EQ Paste
Anthelcide EQ Paste Uses, Dosage, Side Effects, Food Interaction and all others data.
Anthelcide EQ Paste is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.
| Trade Name | Anthelcide EQ Paste |
| Generic | Oxibendazole |
| Oxibendazole Other Names | Oxibendazole, Oxibendazolo, Oxibendazolum |
| Type | For animal use only |
| Formula | C12H15N3O3 |
| Weight | Average: 249.2658 Monoisotopic: 249.111341361 |
| Groups | Investigational, Vet approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | United States |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in infectious and parasitic disease (unspecified) and pediatric indications.
How Anthelcide EQ Paste works
Anthelcide EQ Paste causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies.
Innovators Monograph
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