Anthim
Anthim Uses, Dosage, Side Effects, Food Interaction and all others data.
Anthim, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin. Anthim is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis toxin. It has an approximate molecular weight of 148 kDa.
Trade Name | Anthim |
Generic | Obiltoxaximab |
Obiltoxaximab Other Names | Obiltoxaximab |
Type | Intravenous |
Weight | 148000.0 Da |
Groups | Approved |
Therapeutic Class | |
Manufacturer | |
Available Country | United States, |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Anthim is a monoclonal antibody used for prophylaxis or treatment of inhalational anthrax.
Investigated for use/treatment in anthrax exposure, bacterial infection, crohn's disease, and graft versus host disease.
Anthim is also used to associated treatment for these conditions: Inhaled anthrax caused by Bacillus anthracis
How Anthim works
ETI-204 is an affinity-enhanced, de-immunized antibody, which means that its ability to bind to its target pathogen has been strengthened and that elements that might cause an immune response have been removed. ETI-204 targets and binds to Protective Antigen, which prevents the anthrax toxins from binding to and entering the cells in the body, thereby preventing death.
Food Interaction
No interactions found.Innovators Monograph
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