Apoptone Uses, Dosage, Side Effects and more
| Trade Name | Apoptone |
| Generic | Apoptone |
| Type | |
| Formula | C21H32O2 |
| Weight | Average: 316.485 Monoisotopic: 316.24023027 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in cancer/tumors (unspecified).
How Apoptone works
HE3235 is a second generation antitumor agent that causes apoptosis (cell death). HE3235 inhibits the BCL2 gene which translates proteins that prevent apoptosis and stimulates the expression proteins that induce apoptosis. HE3235 also downregulates the gene that codes for the multi-drug resistant protein ABCG2 (BCRP1 – Breast Cancer Resistance Protein1).
