Arylacenamide
Arylacenamide Uses, Dosage, Side Effects, Food Interaction and all others data.
Arylacenamide (SR31747) is a peripheral [sigma] ligand that binds four proteins in human cells, i.e. SRBP-1, [sigma]-2, HSI and its relative SRBP-2. It is a dual agent with both immunomodulatory and antiproliferative activities.
| Trade Name | Arylacenamide |
| Generic | Arylacenamide |
| Type | |
| Formula | C23H35Cl2N |
| Weight | Average: 396.437 Monoisotopic: 395.214655539 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in cancer/tumors (unspecified), immunosuppressive, and prostate cancer.
How Arylacenamide works
SR31747 blocks proliferation of human lymphocytes, modulates the expression of pro- and anti-inflammatory cytokines, and was shown to protect animals in vivo against acute and chronic inflammatory conditions such as acute graft-versus-host reaction, lethality induced by staphylococcal enterotoxin B and lipopolysaccharide or rheumatoid arthritis. Besides these immunomodulatory activities, the molecule also inhibits the proliferation of various tumor cell lines in vitro in a time- and concentration-dependent manner.
Innovators Monograph
You find simplified version here Arylacenamide
