Arylacenamide

Arylacenamide Uses, Dosage, Side Effects, Food Interaction and all others data.

Arylacenamide (SR31747) is a peripheral [sigma] ligand that binds four proteins in human cells, i.e. SRBP-1, [sigma]-2, HSI and its relative SRBP-2. It is a dual agent with both immunomodulatory and antiproliferative activities.

Trade Name Arylacenamide
Generic Arylacenamide
Type
Formula C23H35Cl2N
Weight Average: 396.437
Monoisotopic: 395.214655539
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Arylacenamide
Arylacenamide

Uses

Investigated for use/treatment in cancer/tumors (unspecified), immunosuppressive, and prostate cancer.

How Arylacenamide works

SR31747 blocks proliferation of human lymphocytes, modulates the expression of pro- and anti-inflammatory cytokines, and was shown to protect animals in vivo against acute and chronic inflammatory conditions such as acute graft-versus-host reaction, lethality induced by staphylococcal enterotoxin B and lipopolysaccharide or rheumatoid arthritis. Besides these immunomodulatory activities, the molecule also inhibits the proliferation of various tumor cell lines in vitro in a time- and concentration-dependent manner.

Innovators Monograph

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