Asimadoline
Asimadoline Uses, Dosage, Side Effects, Food Interaction and all others data.
Asimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis. Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. It has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients and has the potential for treating other gastrointestinal diseases.
| Trade Name | Asimadoline |
| Generic | Asimadoline |
| Asimadoline Other Names | Asimadoline |
| Type | |
| Formula | C27H30N2O2 |
| Weight | Average: 414.5393 Monoisotopic: 414.230728214 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in irritable bowel syndrome (IBS).
How Asimadoline works
Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. Kappa opioid receptors are found mostly in the digestive tract and are believed to play an important role in control of visceral pain and bowel motility. As such, kappa opioid agonists are ideal candidates to relieve the pain, discomfort an impaired motility common to IBS and other gastrointestinal disorders.
Innovators Monograph
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