Balarsen Uses, Dosage, Side Effects and more
Balarsen (INN) is an antiprotozoal agent that was first synthesized by Ernst A.H. Friedheim in 1949 via the complexing of acetarsol with 2,3-dimercaptopropanol. It has since been demonstrated that the agent possesses activity against amoebas and yaws. Considered well tolerated when compared to other related trivalent organoarsenicals, arsthinol has even undergone recent studies as a potential anticancer agent.
Trade Name | Balarsen |
Generic | Arsthinol |
Arsthinol Other Names | Arsthinenol, Arsthinol |
Type | |
Formula | C11H14AsNO3S2 |
Weight | Average: 347.285 Monoisotopic: 346.963106116 |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | January 7, 2025 at 1:49 am |
Uses
Antiprotozoal agent effective against amoebiasis and yaws.
Toxicity
Oral,mouse: LD50 = 300 mg/kg; Oral, rabbit: LD50 = 3200 mg/kg; Oral, rat: LD50 = 980 mg/kg.