Becatecarin Uses, Dosage, Side Effects and more
Becatecarin is a derivative of rebeccamycin.
| Attribute | Details |
|---|---|
| Trade Name | Becatecarin |
| Generic | Becatecarin |
| Becatecarin Other Names | Becatecarin |
| Type | |
| Formula | C33H34Cl2N4O7 |
| Weight | Average: 669.56 Monoisotopic: 668.1804549 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in cancer/tumors (unspecified), liver cancer, gastric cancer, and leukemia (unspecified).
How Becatecarin works
Becatecarin is a small molecule, anticancer compound for the treatment of hepatobiliary duct tumors, a rare and aggressive form of cancer with a high medical need and very limited survival. Becatecarin intercalates into DNA and stabilizes the DNA-topoisomerase I complex, thereby interfering with the topoisomerase I-catalyzed DNA breakage-reunion reaction and initiating DNA cleavage and apoptosis.
