Becatecarin
Becatecarin Uses, Dosage, Side Effects, Food Interaction and all others data.
Becatecarin is a derivative of rebeccamycin.
Trade Name | Becatecarin |
Generic | Becatecarin |
Becatecarin Other Names | Becatecarin |
Type | |
Formula | C33H34Cl2N4O7 |
Weight | Average: 669.56 Monoisotopic: 668.1804549 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in cancer/tumors (unspecified), liver cancer, gastric cancer, and leukemia (unspecified).
How Becatecarin works
Becatecarin is a small molecule, anticancer compound for the treatment of hepatobiliary duct tumors, a rare and aggressive form of cancer with a high medical need and very limited survival. Becatecarin intercalates into DNA and stabilizes the DNA-topoisomerase I complex, thereby interfering with the topoisomerase I-catalyzed DNA breakage-reunion reaction and initiating DNA cleavage and apoptosis.
Innovators Monograph
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