Bemotrizinol

Bemotrizinol Uses, Dosage, Side Effects, Food Interaction and all others data.

Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. Compared to older broad-spectrum chemical agents, bemotrizinol is more more fat soluble (oil soluble in cosmetic oils) to aid in efficacy and broad-spectrum activity . It is claimed to be photostable, which increases its onset of action and its efficiency in providing protection against UV-rays upon topical application . Bemotrizinol is commonly marketed as Tinosorb S and Escalol S.

Findings from an immature rat uterotrophic competitive binding assay suggest that bemotrizinol does not display significant binding affinities towards estrogen and androgen receptors in vitro, thus lacking intrinsic estrogenic, antiestrogenic, androgenic and antiandrogenic activity . Bemotrizinol minimizes erythema and provides excellent anti-aging effects as well as protectant effects on the skin's antioxidant defense system . In a comparative study of individuals with a history of polymorphic light eruption (PLE) undergoing photoprovocation, treatment of bemotrinizol was effective in preventing the development of PLE .

Trade Name Bemotrizinol
Generic Bemotrizinol
Bemotrizinol Other Names Bemotrizinol, BEMT
Type
Formula C38H49N3O5
Weight Average: 627.826
Monoisotopic: 627.36722169
Protein binding

No pharmacokinetic data available.

Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Bemotrizinol
Bemotrizinol

Uses

Bemotrizinol is an ingredient used in sunscreen to block UVA and UVB radiation.

Indicated as an active sunscreen agent.

Bemotrizinol is also used to associated treatment for these conditions: Sunburn

How Bemotrizinol works

By absorbing UV-A and UVB rays ranging from 280 to 400nm, bemotrizinol serves to prevent the formation of free radicals induced by UV radiation .

Toxicity

Oral LD50 in rat is > 2000 mg/kg and dermal LD50 in rabbit is > 2000 mg/kg, respectively .

Food Interaction

No interactions found.

Volume of Distribution

No pharmacokinetic data available.

Elimination Route

No pharmacokinetic data available.

Half Life

No pharmacokinetic data available.

Clearance

No pharmacokinetic data available.

Elimination Route

No pharmacokinetic data available.

Innovators Monograph

You find simplified version here Bemotrizinol

*** Taking medicines without doctor's advice can cause long-term problems.
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