Bentiromide
Bentiromide Uses, Dosage, Side Effects, Food Interaction and all others data.
Bentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy. It is typically administered orally. Cases of headache and gastrointestinal disturbances have been reported with the use of bentiromide. Bentiromide is currently not available in the U.S. or Canada.
Bentiromide is a peptide used as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. The amount of p-aminobenzoic acid and its metabolites excreted in the urine is the quantitative measure of the chymotrypsin-secreting activity of the pancreas.
Trade Name | Bentiromide |
Generic | Bentiromide |
Bentiromide Other Names | Bentiromide, Bentiromido, Bentiromidum, BTPABA |
Type | |
Formula | C23H20N2O5 |
Weight | Average: 404.4153 Monoisotopic: 404.13722176 |
Groups | Investigational, Withdrawn |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Indicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.
How Bentiromide works
Bentiromide is a peptide that is broken down in the pancreas by chymotrypsin. By determining the output of unchanged bentiromide in the urine following oral administration, it is possible to determine the sufficiency of pancreatic activity.
Toxicity
Symptoms of overdose include shortness of breath and troubled breathing.
Innovators Monograph
You find simplified version here Bentiromide