Bentiromido Uses, Dosage, Side Effects and more
Bentiromido is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy. It is typically administered orally. Cases of headache and gastrointestinal disturbances have been reported with the use of bentiromide. Bentiromido is currently not available in the U.S. or Canada.
Bentiromido is a peptide used as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. The amount of p-aminobenzoic acid and its metabolites excreted in the urine is the quantitative measure of the chymotrypsin-secreting activity of the pancreas.
| Trade Name | Bentiromido |
| Generic | Bentiromide |
| Bentiromide Other Names | Bentiromide, Bentiromido, Bentiromidum, BTPABA |
| Type | |
| Formula | C23H20N2O5 |
| Weight | Average: 404.4153 Monoisotopic: 404.13722176 |
| Groups | Investigational, Withdrawn |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Indicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.
How Bentiromido works
Bentiromido is a peptide that is broken down in the pancreas by chymotrypsin. By determining the output of unchanged bentiromide in the urine following oral administration, it is possible to determine the sufficiency of pancreatic activity.
Toxicity
Symptoms of overdose include shortness of breath and troubled breathing.
