Butyrylfentanyl
Butyrylfentanyl Uses, Dosage, Side Effects, Food Interaction and all others data.
Butyrylfentanyl or butyrylfentanyl (not to be confused with 3-methylfentanyl) is a potent short-acting synthetic opioid analgesic drug. It is an analog of fentanyl with roughly 1/30 the potency. Butyrylfentanyl was first synthesized in 1961 by Janssen Pharmaceuticals as a new opioid analgesic.
Butyrylfentanyl has no current legitimate clinical applications, but anecdotal reports indicate it may occasionally be surfacing on the grey-market as a recreational drug. This compound is a schedule I controlled substance in the USA because it is a positional isomer of 3-Methylfentanyl.
The DEA in the United States has confirmed at least 40 fatalities involving butyrfentanyl before May 2016.
| Trade Name | Butyrylfentanyl |
| Generic | Butyrfentanyl |
| Butyrfentanyl Other Names | Butyr-fentanyl, Butyrylfentanyl |
| Type | |
| Formula | C23H30N2O |
| Weight | Average: 350.506 Monoisotopic: 350.235813594 |
| Protein binding | Protein binding studies for butyrfentanyl have not been performed but due to its structural similarity with fentanyl it is likely highly bound to serum albumin and alpha-1-acid glycoprotein in circulation. |
| Groups | Illicit |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Butyrylfentanyl is a methylated fentanyl analog with no clinical indications but is commonly used as a recreational drug.
Butyrylfentanyl was investigated as a potential opioid analgesic but is no longer used for this purpose. It is more often being used as a recreational drug.
How Butyrylfentanyl works
Butyrylfentanyl is a ยต opioid receptor agonist similar to fentanyl.
Toxicity
The LD50 of butyrfentanyl is not readily available.
Patients experiencing an overdose may present with sedation, altered mental state, and difficulty breathing. Symptoms of overdose may be treated with naloxone and supportive measures.
Food Interaction
No interactions found.Volume of Distribution
Data for the volume of distribution of butyrfentanyl are not readily available.
Elimination Route
Data for the absorption of butyrfentanyl are not readily available.
Half Life
Data for the half life of butyrfentanyl are not readily available.
Clearance
Data for the clearance of butyrfentanyl are not readily available.
Elimination Route
The route of elimination of butyrfentanyl has not been well described in the literature but most opioids are mainly eliminated in the urine.
Innovators Monograph
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