Calcium D-gluconate Lactobionate

Calcium D-gluconate Lactobionate Uses, Dosage, Side Effects, Food Interaction and all others data.

Calcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.

Calcium D-gluconate Lactobionate
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Calcium D-gluconate Lactobionate
Generic	Calcium glubionate anhydrous
Calcium glubionate anhydrous Other Names	Calcium D-gluconate lactobionate, Glubionate calcium
Type
Formula	C₁₈H₃₂CaO₁₉
Weight	Average: 592.513 Monoisotopic: 592.1163697
Protein binding	~40%, primarily to albumin
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Calcium glubionate is a calcium salt indicated in the treatment of hypocalcemia, hyperkalemia, lead poisoning, and as an adjunct in the treatment of exudative skin conditions.

Calcium glubionate is indicated to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough calcium (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone).

Calcium D-gluconate Lactobionate is also used to associated treatment for these conditions: Calcium Deficiency, Exudative skin conditions, Fluoride Poisoning, Hypocalcemia, Severe hyperkalemia

How Calcium D-gluconate Lactobionate works

Essential for nervous, muscular, and skeletal systems. Maintain cell membrane and capillary permeability. Act as an activator in the transmission of nerve impulses and contraction of cardiac, skeletal, and smooth muscle. Essential for bone formation and blood coagulation.

Toxicity

Assess patient for nausea, vomiting, anorexia, thirst, severe constipation, paralytic ileus, and bradycardia

Volume of Distribution

Primarily in bones, teeth

Elimination Route

Minimal unless chronic, high doses; absorption predominantly in the duodenum and dependent on calcitriol and vitamin D; mean absorption of calcium intake varies with age (infants 60%, prepubertal children 28%, pubertal children 34%, adults 25%); during pregnancy, calcium absorption doubles; calcium is absorbed in soluble, ionized form; solubility of calcium is increased in an acid environment (IOM 2011); decreased absorption occurs in patients with achlorhydria, renal osteodystrophy, steatorrhea, or uremia