Caldaret
Caldaret Uses, Dosage, Side Effects, Food Interaction and all others data.
Trade Name | Caldaret |
Generic | Caldaret |
Caldaret Other Names | Caldaret |
Type | |
Formula | C11H16N2O3S |
Weight | Average: 256.32 Monoisotopic: 256.088163557 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in heart disease and myocardial infarction.
How Caldaret works
Cardiac damage due to the buildup of sodium (Na+) ischemia and early reperfusion leads to increased calcium (Ca2+) through the reverse mode Na+/Ca2+(NCX) ion exchanger. Caldaret is an intracardiac calcium (Ca2+) handling modulator whose cardioprotective actions are presumed to be due to inhibition of the NCX exhanger and increasing the uptake of Ca2+ via the sarcoplasmic reticulum (SR).
Innovators Monograph
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