Candoxatril
Candoxatril Uses, Dosage, Side Effects, Food Interaction and all others data.
Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
Trade Name | Candoxatril |
Generic | Candoxatril |
Candoxatril Other Names | Candoxatril |
Type | |
Formula | C29H41NO7 |
Weight | Average: 515.6383 Monoisotopic: 515.288302671 |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
How Candoxatril works
Neutral endopeptidase inhibitors such as Candoxatril have a dual mechanism of action. They inhibit two metalloprotease enzymes, neutral endopeptidase and ACE, resulting in an increased availability of natriuretic peptides that exhibit vasodilatory effects and, possibly, tissue protective effects.
Innovators Monograph
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