Candoxatril Uses, Dosage, Side Effects and more
Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
| Trade Name | Candoxatril |
| Generic | Candoxatril |
| Candoxatril Other Names | Candoxatril |
| Type | |
| Formula | C29H41NO7 |
| Weight | Average: 515.6383 Monoisotopic: 515.288302671 |
| Groups | Experimental |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
How Candoxatril works
Neutral endopeptidase inhibitors such as Candoxatril have a dual mechanism of action. They inhibit two metalloprotease enzymes, neutral endopeptidase and ACE, resulting in an increased availability of natriuretic peptides that exhibit vasodilatory effects and, possibly, tissue protective effects.
