CAP-1002
CAP-1002 Uses, Dosage, Side Effects, Food Interaction and all others data.
Cardiosphere-derived cells (CDCs) are derived from human neonatal heart tissue with a distinct antigenic profile (CD105+, CD45-, and CD90low). They exert their effects by secreting exosomes: nanometer-sized, membrane-bound vesicles used for the purpose of cell-cell communication. CDCs target multiple cytokine pathways associated with poor outcomes (e.g. TNFa, IFN-y, IL-1B, and IL-15). The anti-inflammatory effects of CDC work through polarizing macrophages and restoring tissue function.
Trade Name | CAP-1002 |
Generic | CAP-1002 |
Type | |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
How CAP-1002 works
Cardiosphere-derived cell exosomes can reduce cardiac scar size, improve myocardial function, and attenuate damaging remodeling that occurs from infections. CAP-1002 was formulated as an intravenous infusion of cardiosphere-derived cells and is currently being investigated as a treatment for critically ill COVID-19 patients.
Innovators Monograph
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