Cefacetrile

Cefacetrile Uses, Dosage, Side Effects, Food Interaction and all others data.

A derivative of 7-aminocephalosporanic acid.

Cefacetrile is effective against many Gram-positive bacterial strains and somewhat less effective against Gram-negative species. It works by inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.

Table Of contents

• Cefacetrile
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Cefacetrile
Generic	Cefacetrile
Cefacetrile Other Names	Cefacetrile, Cefacetrilo, Cefacetrilum, Cephacetrile
Type
Formula	C13H13N3O6S
Weight	Average: 339.324 Monoisotopic: 339.052505853
Protein binding	23 to 38%
Groups	Experimental, Vet approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Cefacetrile is a broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections.

Cefacetrile is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections.

How Cefacetrile works

In vitro tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell wall synthesis. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.

Volume of Distribution

Vd of 0.2 to 0.5L/.kg

Half Life

1.2 hours

Innovators Monograph

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