Cefacetrile

Cefacetrile Uses, Dosage, Side Effects, Food Interaction and all others data.

A derivative of 7-aminocephalosporanic acid.

Cefacetrile is effective against many Gram-positive bacterial strains and somewhat less effective against Gram-negative species. It works by inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.

Cefacetrile
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Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
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Trade Name	Cefacetrile
Generic	Cefacetrile
Cefacetrile Other Names	Cefacetrile, Cefacetrilo, Cefacetrilum, Cephacetrile
Type
Formula	C₁₃H₁₃N₃O₆S
Weight	Average: 339.324 Monoisotopic: 339.052505853
Protein binding	23 to 38%
Groups	Experimental, Vet approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Cefacetrile is a broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections.

Cefacetrile is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections.

How Cefacetrile works

In vitro tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell wall synthesis. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.