Cefacetrilum
Cefacetrilum Uses, Dosage, Side Effects, Food Interaction and all others data.
A derivative of 7-aminocephalosporanic acid.
Cefacetrilum is effective against many Gram-positive bacterial strains and somewhat less effective against Gram-negative species. It works by inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Trade Name | Cefacetrilum |
Generic | Cefacetrile |
Cefacetrile Other Names | Cefacetrile, Cefacetrilo, Cefacetrilum, Cephacetrile |
Type | |
Formula | C13H13N3O6S |
Weight | Average: 339.324 Monoisotopic: 339.052505853 |
Protein binding | 23 to 38% |
Groups | Experimental, Vet approved |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Cefacetrilum is a broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections.
Cefacetrilum is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections.
How Cefacetrilum works
In vitro tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell wall synthesis. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.
Volume of Distribution
Vd of 0.2 to 0.5L/.kg
Half Life
1.2 hours
Innovators Monograph
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