Ceforanide Uses, Dosage, Side Effects and more
Ceforanide is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species.
Ceforanide is a semisynthetic second-generation cephalosporin. The cephalosporins are bactericidal drugs with both gram-positive and gram-negative activity. They inhibit bacterial cell wall synthesis in a way similar to the penicillins.
| Trade Name | Ceforanide |
| Generic | Ceforanide |
| Ceforanide Other Names | Ceforanide, Ceforanido, Ceforanidum |
| Type | |
| Formula | C20H21N7O6S2 |
| Weight | Average: 519.554 Monoisotopic: 519.099472819 |
| Protein binding | 80.6% |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
For the treatment of infections caused by susceptible organisms.
How Ceforanide works
The bactericidal activity of ceforanide results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).
Toxicity
Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Elimination Route
Rapidly absorbed following intramuscular injection.
Half Life
2.6 to 2.98 hours
