Ceforanidum
Ceforanidum Uses, Dosage, Side Effects, Food Interaction and all others data.
Ceforanidum is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species.
Ceforanidum is a semisynthetic second-generation cephalosporin. The cephalosporins are bactericidal drugs with both gram-positive and gram-negative activity. They inhibit bacterial cell wall synthesis in a way similar to the penicillins.
Trade Name | Ceforanidum |
Generic | Ceforanide |
Ceforanide Other Names | Ceforanide, Ceforanido, Ceforanidum |
Type | |
Formula | C20H21N7O6S2 |
Weight | Average: 519.554 Monoisotopic: 519.099472819 |
Protein binding | 80.6% |
Groups | Approved |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of infections caused by susceptible organisms.
How Ceforanidum works
The bactericidal activity of ceforanide results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).
Toxicity
Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Elimination Route
Rapidly absorbed following intramuscular injection.
Half Life
2.6 to 2.98 hours
Innovators Monograph
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