CEP-1347
CEP-1347 Uses, Dosage, Side Effects, Food Interaction and all others data.
CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults leading to programmed cell death (apoptosis) which could improve the survival of dopamine neurons prior to and after transplantation.
Trade Name | CEP-1347 |
Generic | CEP-1347 |
Type | |
Formula | C33H33N3O5S2 |
Weight | Average: 615.762 Monoisotopic: 615.186162561 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in asthma and parkinson's disease.
How CEP-1347 works
CEP-1347, an orally active molecule, is a selective and potent inhibitor of the stress-activated protein kinase pathway, an intracellular signaling pathway that is an essential component of the stress response leading to neuronal death. In-vitro cell culture systems and in-vivo mouse and non-human primate models of Parkinson's disease have shown that CEP-1347 protects dopamine neurons in the substantia nigra, the area of the brain affected by Parkinson's disease.
Innovators Monograph
You find simplified version here CEP-1347