Chlorprothixen Zentiva
Chlorprothixen Zentiva Uses, Dosage, Side Effects, Food Interaction and all others data.
Chlorprothixen Zentiva is a typical antipsychotic drug of the thioxanthene (tricyclic) class. Chlorprothixen Zentiva exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.
Chlorprothixen Zentiva is a typical antipsychotic drug of the thioxanthine class. It has a low antipsychotic potency (half to 2/3 of chlorpromazine). Chlorprothixen Zentiva has not thoroughly demonstrated an antidepressant or analgesic effect but it has demonstrated antiemetic effects. It is used in the treatment of nervous, mental, and emotional conditions. Improvement in such conditions is thought to result from the effect of the medicine on nerve pathways in specific areas of the brain. Chlorprothixen Zentiva has a similar side effect profile to chlorpromazine, though allergic side effects and liver damage are less frequent.
Trade Name | Chlorprothixen Zentiva |
Generic | Chlorprothixene |
Chlorprothixene Other Names | Chlorprothixen, Chlorprothixene, Chlorprothixine, Chlorprotixen, Chlorprotixene, Chlorprotixine, Chlothixen |
Type | |
Formula | C18H18ClNS |
Weight | Average: 315.86 Monoisotopic: 315.0848485 |
Groups | Approved, Experimental, Investigational, Withdrawn |
Therapeutic Class | |
Manufacturer | |
Available Country | Bulgaria, Poland, Russia |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Chlorprothixen Zentiva is a thioxanthene antipsychotic.
For treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
Chlorprothixen Zentiva is also used to associated treatment for these conditions: Psychosis, Schizophrenia
How Chlorprothixen Zentiva works
Chlorprothixen Zentiva blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.
Toxicity
Symptoms of overdose include difficulty in breathing (severe), dizziness (severe), drowsiness (severe), muscle trembling, jerking, stiffness, or uncontrolled movements (severe), small pupils, unusual excitement, and unusual tiredness or weakness (severe).
Food Interaction
- Avoid alcohol.
- Take with food. Food reduces irritation.
Elimination Route
Incomplete bioavailability.
Half Life
8 to 12 hours
Innovators Monograph
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