Cixutumumab

Cixutumumab Uses, Dosage, Side Effects, Food Interaction and all others data.

Cixutumumab has been used in trials studying the treatment of Lung Cancer, Malignant Neoplasm, Leukemia, Mast-Cell, Non-Small-Cell Lung Carcinoma, and Adenocarcinoma of the Prostate.

Cixutumumab is a highly specific recombinant human monoclonal antibody with high affinity for the insulin-like growth factor-I receptor (IGF-IR). IGF-IR is overexpressed in a variety of tumour types.

Trade Name Cixutumumab
Generic Cixutumumab
Cixutumumab Other Names Cixutumumab
Type
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Cixutumumab
Cixutumumab

How Cixutumumab works

Cixutumumab is a fully human monoclonal antibody that specifically targets the type 1 human insulin-like growth factor receptor (IGF-IR). Tumors have receptors for the insulin-like growth factor-1 (IGF-I), and it is thought that the presence of these receptors cause tumors to grow. Cixutumumab attaches to the receptors and may inhibit the growth of cancer cells.

Half Life

148 h (3 mg/kg dose level) 209 h (6mg/kg dose level)

Innovators Monograph

You find simplified version here Cixutumumab

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