Colupressine

Colupressine Uses, Dosage, Side Effects, Food Interaction and all others data.

A synthetic nonapeptide comprising cysteinyl, phenylalanyl, phenylalanyl, glutaminyl, asparaginyl, cysteinyl, prolyl, lysyl, and glycinamide residues in sequence, with a disulfide bridge joining the two cysteine residues. Its antidiuretic effects are less than those of vasopressin. It is a non-catecholamine vasoconstrictor used in local anaesthetic injections for dental use, and is an ingredient of preparations that have been used for treatment of pain and inflammation of the mouth.

Colupressine is a synthetic analog of lypressin or vasopressin with a greater vasoconstrictor activity than antidiuretic action. It is used primarily as a hemostatic.

Trade Name Colupressine
Generic Felypressin
Felypressin Other Names Felipresina, Felypressin, Felypressine, Felypressinum, PLV-2
Type
Formula C46H65N13O11S2
Weight Average: 1040.219
Monoisotopic: 1039.436791367
Groups Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Colupressine
Colupressine

Uses

For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential.

How Colupressine works

Colupressine binds to the vasopressin receptor V1a. This causes contraction of the smooth muscle in the vascular bed, especially capillaries, small arterioles and venules.

Innovators Monograph

You find simplified version here Colupressine

*** Taking medicines without doctor's advice can cause long-term problems.
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