Concentrat vo34
Concentrat vo34 Uses, Dosage, Side Effects, Food Interaction and all others data.
Concentrat vo34 is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a sedative and antiemetic.
Concentrat vo34 is one of the phenothiazine derivative psychotropic drugs. Concentrat vo34 has actions at all levels of the central nervous system-primarily at subcortical levels-as well as on multiple organ systems. Concentrat vo34 has strong antiadrenergic and weaker peripheral anticholinergic activity; ganglionic blocking action is relatively slight. It also possesses slight antihistaminic and antiserotonin activity.
| Trade Name | Concentrat vo34 |
| Generic | Acepromazine |
| Acepromazine Other Names | Acepromazina, Acepromazine, Acepromazinum, Acetazine, Acetopromazine, Acetylpromazine |
| Type | |
| Formula | C19H22N2OS |
| Weight | Average: 326.456 Monoisotopic: 326.145284026 |
| Groups | Experimental, Vet approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Concentrat vo34 was first used in humans in the 1950s as an antipsychotic agent. It is now rarely used in humans. Concentrat vo34 is frequently used in animals as a sedative and antiemetic. Its principal value is in quietening and calming anxious animals.
How Concentrat vo34 works
Concentrat vo34 acts as an antagonist (blocking agent) on different postsysnaptic receptors -on dopaminergic-receptors (subtypes D1, D2, D3 and D4 - different antipsychotic properties on productive and unproductive symptoms), on serotonergic-receptors (5-HT1 and 5-HT2, with anxiolytic, antidepressive and antiaggressive properties as well as an attenuation of extrapypramidal side-effects, but also leading to weight gain, fall in blood pressure, sedation and ejaculation difficulties), on histaminergic-receptors (H1-receptors, sedation, antiemesis, vertigo, fall in blood pressure and weight gain), alpha1/alpha2-receptors (antisympathomimetic properties, lowering of blood pressure, reflex tachycardia, vertigo, sedation, hypersalivation and incontinence as well as sexual dysfunction, but may also attenuate pseudoparkinsonism - controversial) and finally on muscarinic (cholinergic) M1/M2-receptors (causing anticholinergic symptoms like dry mouth, blurred vision, obstipation, difficulty/inability to urinate, sinus tachycardia, ECG-changes and loss of memory, but the anticholinergic action may attenuate extrapyramidal side-effects).
Toxicity
Agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, restlessness
Food Interaction
- Avoid alcohol.
- Take with food. Food reduces irritation.
Half Life
3 hours in horses.
Innovators Monograph
You find simplified version here Concentrat vo34
